• BIOL1414
  • Biochem & Molecular Biology

  • Credits (ECTS): 10
  • Biological Sciences

Modules are delivered
as part of a programme.
To apply for the
programme,
see the DIT website

Overview

Module Description

This foundational module will provide learners with a general introduction to the molecular and biochemical principles upon which cells depend. It plays an essential role in establishing knowledge of the key chemical and cellular structures of life such as carbohydrates, proteins, nucleic acids, lipids and subcellular organisation. It will also introduce key biochemical concepts relating to bioenergetics, enzyme kinetics, inheritance, transcription and translation.

Indicative Syllabus

Lectures
Introduction to the cell
Subcellular organisation of the cell
Essential chemistry for biologists
Biochemistry of carbohydrates, proteins, nucleic acids and lipids
Cellular macrosctructures (e.g. nucleosome, ribosome)
Transcription and translation
Enzyme biochemistry
Enzyme kinetics
Introductory bioenergetics
Basic patterns of inheritance (e.g. Mendelian, X-linked)
Molecular basis of inheritance of traits
Practicals
Microscopy as a tool in biology
Analysis of biomolecules by spectroscopy
Application of electrophoretic techniques to the analysis of biomolecules
Extraction, purification and quantification of DNA
Extraction, purification and quantification of RNA
Extraction, purification and quantification an enzyme protein (e.g. alkaline phosphatase)
Determination of the Km, Vmax and kcat of an enzyme
Identification of an enzyme inhibitor using a screening approach
Determination of a cytogenetic karyotype

ISCED:0512: Biochemistry
Total Contact Teaching Hours:76

Please note that the catalogue is provided as a guide to modules in DIT. Not all modules listed will necessarily be offered every year and new modules may also be added. Information subject to change. For detail on specific programmes/modules please contact the relevant School directly.