• TFBC2002
• Biochemistry 2

This module integrates the different components of intermediary metabolism. Emphasis will be placed on describing the physiological ramifications of alterations in substrate load, especially those induced by dietary modification. The function and regulatory role of macro and micro nutrients will be stressed. Conditions with particular relevance to clinical nutrition are emphasized.

The aim of this module is to understand the main metabolic pathways and the mechanisms of control and regulation, and the importance of these metabolic pathways from a nutritional point of view. Also important is to develop skills in analytical techniques and procedures used in biochemistry.

Bioenergetic principles.
Biological reactions and compounds rich in energy.
Carbohydrates: Glycolisis, pentoses pathway, hexoses patwhay, TCA cycle, gluconeogenesis and glucogenolysis.
Cholesterol metabolism.
Fermentation.
Glycerol and fatty acid metabolism.
Hormonal regulation control.
Introduction of metabolism study.
Ketogenesis.
Levels of regulation.
Lipids: Digestion, absorption and transport.
Metabolic pathways.
Metabolic regulation.
Metabolism of carbohydrates and nutritional implications.
Metabolism overview and integration.
Nutritional and metabolic regulation.
Oxidative phosphorylation and electron transport chain.
PCR principles.
Second messengers.